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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF2C
All Species:
21.21
Human Site:
S118
Identified Species:
46.67
UniProt:
Q99661
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99661
NP_006836.2
725
81313
S118
S
T
R
M
S
T
V
S
E
L
R
I
T
A
Q
Chimpanzee
Pan troglodytes
XP_001151337
725
81253
S118
S
T
R
M
S
T
V
S
E
L
R
V
T
A
Q
Rhesus Macaque
Macaca mulatta
XP_001093746
706
79332
S99
S
T
R
M
S
T
V
S
E
L
R
V
T
A
Q
Dog
Lupus familis
XP_532606
723
81259
S116
S
T
R
M
S
T
V
S
E
V
R
I
T
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q922S8
721
81067
S115
S
T
R
M
S
T
V
S
E
V
R
I
P
A
Q
Rat
Rattus norvegicus
Q62909
671
75553
T104
R
P
S
C
S
T
V
T
E
L
P
L
L
M
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506273
959
105390
S205
I
D
L
E
S
I
F
S
L
N
P
D
L
A
P
Chicken
Gallus gallus
Q5ZKV8
706
79845
T97
K
I
V
K
G
R
R
T
V
A
P
V
K
N
D
Frog
Xenopus laevis
Q91636
730
82567
Q118
L
L
S
E
S
G
A
Q
S
V
L
R
E
R
S
Zebra Danio
Brachydanio rerio
NP_001108065
689
76957
R118
P
S
R
R
M
T
T
R
Q
T
C
L
F
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960Z0
805
88653
G139
N
S
N
T
T
A
G
G
G
G
G
T
T
T
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.4
91.7
N.A.
87.5
81
N.A.
41.5
54.3
62.5
49.9
N.A.
44.2
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
96.5
96
N.A.
92.8
86.7
N.A.
55
72.5
78.4
66.4
N.A.
60.2
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
86.6
N.A.
86.6
33.3
N.A.
20
0
6.6
20
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
46.6
N.A.
20
13.3
13.3
40
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
0
0
10
0
0
0
46
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
10
% D
% Glu:
0
0
0
19
0
0
0
0
55
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
10
10
10
10
10
10
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
10
0
0
0
0
0
28
0
0
10
% I
% Lys:
10
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
10
10
10
0
0
0
0
0
10
37
10
19
19
0
0
% L
% Met:
0
0
0
46
10
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
10
0
10
0
0
0
0
0
0
10
0
0
0
10
0
% N
% Pro:
10
10
0
0
0
0
0
0
0
0
28
0
10
0
10
% P
% Gln:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
55
% Q
% Arg:
10
0
55
10
0
10
10
10
0
0
46
10
0
19
0
% R
% Ser:
46
19
19
0
73
0
0
55
10
0
0
0
0
0
19
% S
% Thr:
0
46
0
10
10
64
10
19
0
10
0
10
46
19
0
% T
% Val:
0
0
10
0
0
0
55
0
10
28
0
28
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _